"Hello Mr. Beck, the manufacture of the blister film is similar to other common medical products as blood bag, IV therapies or peritoneal dialysis bags. These bags are manufactured by thermosealed. During the manufacture process is commonly attached one or several PVC tubing. In this case, the needle is attached to a PVC piece, like a normal needle for a conventional syringe, and this piece is sealed as the tubes in the blood bags.I hope I have clarified your doubts. If you need more explanation please feel free to write me. horaciopacebedetti@gmail.com"